Author

Xiang-Tao Zhu

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Open access Sep 2026

Establishment of an ex vivo vascular tissue model to investigate bunyavirus-triggered vascular endothelial injury

ABSTRACT Severe fever with thrombocytopenia syndrome, an emerging infectious disease caused by the tick-borne bunyavirus severe fever with thrombocytopenia syndrome virus (SFTSV), is associated with a high clinical fatality rate of 12%–50%. Vascular endothelial injury triggered by SFTSV infection has been linked to sev...

Zi-Han Guan, Xi Chen, Yu-Jie Fang et al. · mBio · 0 citations

Open access Sep 2026

A859L Plays a Critical Role in Facilitating Efficient African Swine Fever Virus Replication

African swine fever virus (ASFV) is a highly pathogenic agent that poses a severe threat to the global swine industry. The biological function of A859L, an ASFV-encoded RNA helicase, remains largely elusive. Here, we show that A859L is highly conserved across diverse ASFV isolates and belongs to the SF2 superfamily of...

Xiang-Tao Zhu, Hong-Yu Yan, Wan-Hui Zhou et al. · Viruses · 0 citations