Author

Xiang-Xiang Wang

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Preprint Sep 2026

Data-Adaptive Grassmann Manifold Representations for Spatial Transcriptomics Alignment

Spatial transcriptomics measures gene expression together with spatial coordinates, but many existing analysis methods represent each spot primarily by a single feature vector. We propose GrassST, a subspace method for spatial transcriptomics analysis and cross-slice alignment. For each spatial spot, GrassST constructs...

Xiang-Xiang Wang, Sean Cottrell, Guo-Wei Wei · 0 citations

Preprint Sep 2026

GrassTop: Grassmannian k-mer Topology for Viral Classification and Phylogenetic Analysis

We introduce GrassTop, a genome representation that integrates Grassmann manifolds and algebraic topology for viral classification and phylogenetic analysis. The framework begins by constructing multiscale topological and spectral descriptors of (k)-mer positional patterns. It then extracts a low-rank subspace that sum...

Xiang-Xiang Wang, Guo-Wei Wei · 0 citations