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Author

Xiang Yao

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Review Open access Oct 2026

The effect of sequential antiresorptive therapy after denosumab discontinuation on fracture risk: a systematic review and meta-analysis

Discontinuation of denosumab (DMAb) causes a rapid rebound in bone turnover and increases the risk of multiple vertebral fractures. However, the optimal sequential antiresorptive strategy and its specific timing remain uncertain. We systematically searched PubMed, Embase, Web of Science, and Cochrane Libra...

Qi-Wen Bao, Xuan Tang, Han Miao et al. · 0 citations
Review Open access Sep 2026

Artificial Intelligence‐Driven Precision Bisphosphonate Therapy in Osteoporosis: Mechanisms, Clinical Applications, Risks, and Future Directions

ABSTRACT Bisphosphonates remain the pharmacological standard of care for osteoporosis; however, their clinical efficacy is limited by significant diagnostic gaps, heterogeneous therapeutic responses, and persistent concerns regarding long‐term safety, including medication‐related osteonecrosis of the jaw (MRONJ) and at...

Xiang Yao, Yi-Cong Chao, Xiao Gu et al. · 0 citations

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