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Xiao-Bing Chen

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Oct 2026

RNA-Lipid Interactions Control Structure and Dynamics of Lipid Nanoparticles

Lipid nanoparticles (LNPs) are the leading platform for RNA delivery, enabling applications ranging from mRNA vaccines to CRISPR therapeutics. Ionizable lipids, such as DLin-MC3-DMA (MC3), play a central role in nucleic acid encapsulation and intracellular delivery, yet the molecular mechanisms governing LNP structur...

Xiao-Bing Chen, Cong Xu, Carlos R. Baiz · 0 citations

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