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Xiao-Cheng Lu

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Aug 2026

Lactate derived from CAFs mediates H3K18la in stemness gene promoters, which promotes tumor malignant phenotype formation

It is demonstrated that lactate derived from CAFs promotes the expression of stemness genes by mediating H3K18 lactylation in the promoters of these genes in NSCLC cells, thereby accelerating the malignant phenotype formation of NSCLC cells.

Jie Yao, Guang-Bing Li, Ke Chen et al. · 0 citations

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