Open access
Sep 2026
The role of apolipoprotein E4 on calcium homeostasis in primary hippocampal neurons: an in vitro study
Background We previously demonstrated that apolipoprotein E (apoE4) accelerates neurodegeneration in a transgenic mouse model, but the mechanism is still unclear. A previous study reported that death-associated protein kinase 1 (DAPK1) interacts with the NR2B subunit of the N-methyl-D-aspartate (NMDA) receptor, this DA...
De-Shan Liu, Yi-Fen Zhuo, Si-Si Chen et al.
· Frontiers in Neuroscience · 0 citations