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Author

Xiaochun Wang

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2 papers indexed here

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Oct 2026

Construction, expression, and immunogenicity analysis of a fusion gene based on the PE/PPE family in combination with adjuvants.

Tuberculosis (TB) remains the leading global cause of death from a single infectious agent and a major fatal infectious disease worldwide. However, the Bacillus Calmette-Guérin (BCG) vaccine-currently the only licensed TB vaccine in clinical practice-has critical limitations in preventing latent infection and disease r...

Xiao-Chun Wang, Ming-Ming Zhou, Li-Fa Xu et al. · 0 citations
Aug 2026

Construction of a subunit vaccine based on Mycobacterium tuberculosis EsxE and evaluation of its immunogenicity and ex vivo mycobacterial growth inhibitory activity

It is demonstrated that rEsxE is immunogenic and that the BCG prime–rEsxE/MnJ boost strategy elicits robust Th1‑biased immune responses as well as ex vivo mycobacterial growth inhibitory function, thereby supporting the further development of this approach as a candidate tuberculosis subunit vaccine.

Run-Lin Wang, Xiao-Chun Wang, Bing-Xin Wang et al. · 0 citations

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