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Xiao-Dong Qin

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Open access Aug 2026

Redox cycling of viral RNA polymerase controls picornavirus replication

Picornaviruses, including foot-and-mouth disease virus (FMDV), enterovirus 71 (EV71) and encephalomyocarditis virus (EMCV), are important pathogens that cause fever, herpes, and myocarditis in humans and animals. The interplay between picornaviruses and their hosts remains enigmatic. Here we perform porcine genome-wide...

Wei-Wei Li, Zhao-Yu Zhu, Wei Zhang et al. · 0 citations
Open access Jan 2026

IRES Mutation Confers a Replicative Advantage to SVA by Enhancing Translation Efficiency

This study aimed to characterize the mutational and evolutionary patterns of the SVA genome during its transmission within host cells exhibiting enhanced innate immunity, and indicated that the mutant virus was unable to evade host antiviral innate immunity, whereas it significantly enhanced the translational activity...

Tao Li, Wen Dang, Wei-Wei Li et al. · 0 citations

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