Preparation of glycyrrhizic acid functionalized nanostructured lipid carrier loaded with tanshinone IIA and its anti-hepatic fibrosis effect.
In this study, the natural active ingredient glycyrrhizic acid (GA) was used to replace traditional synthetic surfactants to construct GA-functionalized Tanshinone IIA (TSA) nanostructured lipid carriers (TSA@GA NLCs). The prepared TSA@GA NLCs had a particle size of 268.7 ± 2.3 nm and an encapsulation efficiency of 84....