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Xiao-Fei Nan

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Sep 2026

Functional group-dependent stabilization and dissociation mechanisms of EGFR allosteric inhibitors.

Allosteric inhibitors targeting the αC-helix-adjacent pocket provide an alternative strategy to overcome resistance associated with ATP-site mutations. However, the structural and thermodynamic determinants governing their stability across resistant EGFR variants remain incompletely understood. Here, we comparatively i...

Amina Tariq, M. Shoaib, Ling-Bo Qu et al. · 0 citations
Open access Jul 2026

Dual Cross-Attention Network for Hierarchical Feature Fusion in Protein-Protein Interaction Prediction

DCAPPI (Dual Cross-Attention network for Protein-Protein Interaction prediction), a novel framework leveraging dual cross-attention modules for hierarchical feature fusion at both intra- and inter-protein levels, achieves superior performance over state-of-the-art methods on benchmark datasets.

Shuai Lu, Yuguang Li, Zhen Tian et al. · 0 citations

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