Sep 2026
The Q653R substitution in the spike protein is associated with attenuation of a GVI-1 infectious bronchitis virus strain.
Yu-Sen Tian, Yuan-Lu Lu, Yi-Ran Zeng et al.
· Avian Pathology · 0 citations
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Sep 2026
Development of a subunit vaccine candidate (RBD-HA trimer) provides dual protection against multi-subtype avian influenza viruses and QX-type infectious bronchitis virus.
Avian influenza virus (AIV) and infectious bronchitis virus (IBV) are major respiratory pathogens of poultry, and their co-circulation complicates disease control. Here, we developed a chimeric subunit vaccine, RBD-HA, in which the receptor-binding domain (RBD) of the QX-type IBV spike protein replaced the immunodomina...
Yi-Qing Zheng, Bing-Chen Qiao, Zi-He Gao et al.
· Vaccine · 0 citations