Open access
Sep 2026
High-throughput label-free single-cell proteomics enabled by multicolumn NanoLC
Mass spectrometry (MS)-based single-cell proteomics (SCP) enables proteome-wide analysis at single-cell resolution, offering insights into cellular heterogeneity, biological processes, and disease mechanisms. However, conventional nanoLC-MS workflows are constrained by long gradients and low throughput, limiting their...
Chao Wang, Hsien-Jung L. Lin, Si-Qi Huang et al.
· Nature Communications · 1 citation