Xiaofeng Zeng

Identification of psoriasis-associated hub genes by integrated transcriptomics and machine learning

This study aims to systematically identify key hub genes in psoriasis pathogenesis through the integration of bioinformatics, machine learning and experimental validation methods, and emerged HPSE emerged as a multifunctional core gene associated with immune dysregulation.

Immunosuppressant-refractory Multifaceted Immune Dysregulations for Systemic Lupus Erythematosus.

While the systemic lupus erythematosus (SLE), a severe autoimmune disease, is known to relapse frequently after treatment, none of the previous single-cell studies have examined the immune dynamics and their potential contribution to this relapse in the real clinical setting. To address this issue, here we employed sin...

Comparative Value of Traditional versus Novel Immune-Inflammatory Indices in Assessing Disease Activity of Sjögren’s Disease: A Multicenter Cohort Study