Author

Xiao-Hua Li

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Open access Oct 2026

Comparative evaluation of metagenomic and targeted next-generation sequencing for pathogen detection in bronchoalveolar lavage fluid from patients with lower respiratory tract infections: a retrospective cohort study

Rapid and precise pathogen identification is crucial for managing lower respiratory tract infections (LRTIs). While metagenomic next-generation sequencing (mNGS) and targeted next-generation sequencing (tNGS) are emerging as valuable diagnostic tools, large-scale studies directly evaluating their real-world impact...

Rui Zhao, He-Ya Na, Wei Miao et al. · Frontiers in Cellular and In... · 0 citations

Open access Aug 2026

A lifestyle-driven inflammatory load index and its circulating metabolomic signature identify susceptibility to hospital-recorded acute respiratory infections: a population-based cohort study of 295,679 adults

In a population-scale cohort, a lifestyle-anchored inflammatory load index showed a graded association with hospital-recorded ARIs, and a circulating NMR-derived MRS, dominated by fatty-acid-related biomarkers and including the established low-grade-inflammation marker glycoprotein acetylation (GlycA), accounted for ap...

Xu-Feng Fu, Xiao-Hua Li, Xin-Qian Ma et al. · Frontiers in Endocrinology · 0 citations