Review
Aug 2026
Mitochondria-centered signalling in pulmonary hypertension: From metabolic reprogramming to vascular remodeling and right ventricular failure.
Pulmonary hypertension (PH) is a progressive cardiopulmonary disorder characterized by pulmonary vascular remodeling, increased pulmonary vascular resistance, and right ventricular failure. Beyond its bioenergetic function, mitochondria act as signalling hubs that integrate metabolic flux, redox homeostasis, calcium ha...
Meng-Jie Zhang, Si-Qin Peng, Na Liang et al.
· Cellular Signalling · 0 citations