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[This corrects the article DOI: 10.1371/journal.pone.0356002.].
Background Inflammatory bowel disease (IBD) and osteoporosis (OP) often co-occur, with IBD accelerating OP onset, though the underlying mechanisms remain unclear. Methods Based on gene expression data from the GEO database, differential expression analysis was performed using the limma package to identify genes dysregu...
The net skeletal effect of the immune system is determined by the balance of interacting cell types, cytokine networks, and signaling pathways, and systematic evaluation of combination strategies pairing immunomodulators with anti-resorptive, anabolic agents, or senolytics.
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