Author

Xiao-Hui Lv

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Review Open access Sep 2026

PD-L1 in Ovarian Cancer: Immune Evasion, Tumor-Intrinsic Signaling, and Chemoresistance.

Epithelial ovarian cancer remains a lethal malignancy, primarily due to late-stage presentation and the frequent development of platinum resistance. While immune checkpoint blockade (ICB) targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) axis has revolutionized oncology, its success...

Zhi-Yang Xu, Xiao-Hui Lv, Yun-Ping Wang et al. · Cancer Medicine · 0 citations

Open access Jul 2026

Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT

The findings suggest that targeting SLC25A46 represents a rational strategy to improve treatment outcomes in OC patients and highlight the critical role of SLC25A46/MARCHF5/CACT axis in facilitating cell proliferation and ferroptosis evasion in OC cells via activating fatty acid oxidation‐mediated ATP and NADPH product...

Yunge Gao, Jiatao Hao, Xiaohong Zhang et al. · Advancement of science · 0 citations