Multifunctional nanoflower-assisted catalytic hairpin assembly enables extracellular vesicles derived-microRNAs profiling for colorectal cancer diagnosis.
The clinical translation of small extracellular vesicle-derived microRNAs (sEV-miRNAs) for early colorectal cancer (CRC) diagnosis is often limited by their low abundance and complexity of biological fluids. Herein, we developed an ultrasensitive electrochemical platform based on multifunctional DNA nanoflower-assisted...