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Author

Xiao-Hui Yan

2 papers indexed here

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Oct 2026

Multifunctional nanoflower-assisted catalytic hairpin assembly enables extracellular vesicles derived-microRNAs profiling for colorectal cancer diagnosis.

The clinical translation of small extracellular vesicle-derived microRNAs (sEV-miRNAs) for early colorectal cancer (CRC) diagnosis is often limited by their low abundance and complexity of biological fluids. Herein, we developed an ultrasensitive electrochemical platform based on multifunctional DNA nanoflower-assisted...

Xiao-He Zhang, Jie-Zhen Pan, Yuan-Hong Lin et al. · 0 citations
Open access Aug 2026

Orthogonal DNA barcoding enables subpopulation-resolved extracellular vesicle miRNA profiling

Extracellular vesicle–associated microRNAs (EV-miRNAs) hold promise for liquid biopsy, but their clinical utility is hindered by EV heterogeneity. Here, we report DEEPER, a DNA-encoded orthogonal recognition platform for selective barcoding of tumor-derived EV subpopulations and in situ miRNA profiling. DEEPER uses fou...

Ye Zhang, Yi-Tong Zhu, Yu Zhang et al. · 1 citation

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