Review
Open access
Sep 2026
Tumor-immune spatiotemporal co-evolution: A new paradigm for understanding and overcoming therapy resistance in metastatic castration-resistant prostate cancer (Review)
S spatiotemporal co-evolution is established as a unifying framework that transforms mCRPC from a uniformly fatal disease into a chronically manageable condition through precisely timed, spatially informed and mechanistically rational interventions.
Li Yan, Xiao-Ke Sun, Peng-Xiao Su
· International Journal of Mol... · 0 citations