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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Xiao-Lei Yao

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Review Open access Sep 2026

Nrf2/HO-1 signaling in retinal neurodegenerative diseases: redox homeostasis, cytoprotection, and therapeutic perspectives

This review critically synthesizes the cytoprotective roles, evidence boundaries, translational challenges, and future directions of Nrf2/HO-1 signaling in RNDs, organized around retinal cell types, redox homeostasis-related injury mechanisms, disease-specific evidence, and intervention strategies.

Yu Tang, Xiao-Lei Yao, Qing-Hua Peng · 0 citations

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