Aug 2026
ROS-responsive hydrogel nanoarmor enables stepwise photodynamic viral inactivation and sustained anti-inflammation for monkeypox therapy.
In mouse, rabbit, and non-human primate models with MPXV-induced skin damage, this hydrogel nanoparticle protective layer significantly inhibits viral replication and accelerates wound healing, representing a transformative, convertible platform for treating MPXV and other highly inflammatory viral infections.
Ning Shi, Xinyu Cao, Xiaolong Zhu et al.
· Biomaterials · 0 citations