Xiao-Ling Wang

FDA-approved Dimethyl Fumarate Targets Thioredoxin Reductase to Induce Apoptosis in Triple-Negative Breast Cancer.

Triple-negative breast cancer (TNBC) is characterized by poor prognosis, which is closely linked to significant tumor heterogeneity and the absence of effective targeted treatments beyond conventional chemotherapy, thereby necessitating the discovery of novel therapeutic options. Altered thioredoxin reductase (TrxR) ac...