Author

Xiaomei Li

2 papers indexed here

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Open access Sep 2026

Multi‐site sequencing supports dual‐track evolution and identifies candidate metastasis‐associated factors in gastric cancer ovarian metastasis

Abstract Background Gastric cancer ovarian metastasis (GCOM) is an aggressive clinical entity whose evolutionary dissemination routes and molecular features remain incompletely defined. Methods We performed whole‐exome sequencing and patient‐level phylogenetic reconstruction of 81 spatially distinct tumour specimens fr...

Pei-Yu Zhu, Xiao-Fang Xing, Ke Ji et al. · Clinical and Translational M... · 0 citations

Open access Jul 2026

Cisplatin-induced ecDNA enhances tumor malignancy and accelerates chemoresistance acquire in gastric cancer.

This study revealed that cisplatin could promote ecDNA generation, which enhanced malignant phenotypes, including cell proliferation, motility and drug resistance, and was associated with poorer patient prognosis, and targeting ecDNA with inhibitors could reverse these effects.

Huanbo Zhu, Lian Chen, Long-Tao Huangfu et al. · Journal of Advanced Research · 0 citations