Review
Aug 2026
CD74 in hematological malignancies: from MHC chaperone to therapeutic target.
Given its expression pattern, along with its swift internalization and limited expression in most normal tissues, CD74 emerges as a promising target for a wide array of therapeutic approaches like antibody-drug conjugates (ADCs), bispecific antibodies, and Chimeric Antigen Receptor T-cell (CAR-T) therapy.
Shuni Zhang, Shuzhen Xiong, Jiajia Cao et al.
· Leukemia and Lymphoma · 0 citations