Open access
Aug 2026
Urolithin A Alleviates Osteonecrosis and Is Associated With Regulation of SIRT3 in Osteoclasts
Background: Urolithin A (UA) is a safe and promising therapeutic strategy for aging-related disorders, including osteoporosis. Sirtuin 3 (SIRT3) has been reported as a potential modulator of bone-joint pathologies such as osteoclast activation. However, whether UA affects osteoclast activation and function through SIRT...
Yi Xue, Dong-Hua Fan, Pu Ying et al.
· Discover medicine · 0 citations