Xiao-Min Gao

A cross-vertebrate single-cell and spatial atlas reveals evolutionary trajectories of gastrointestinal cellular innovation.

The cellular innovations underlying vertebrate gastrointestinal diversification remain largely unknown. Here, we constructed a single-cell and spatial transcriptomic atlas comprising nearly 1 million cells from 10 species, spanning 500 million years of vertebrate evolution. Analysis of conserved gene co-expression modu...