Author

Xiao-Min Yang

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Open access Aug 2026

Calycosin Safeguards Mitochondrial Genomic Stability and Iron Homeostasis via the NRF2/NRF1-TFAM Axis to Mitigate Doxorubicin-Induced Cardiotoxicity

The findings suggest that CAL acts as a dual-regulator of mitochondrial transcriptional machinery and iron metabolism, offering a novel therapeutic strategy to safeguard mitochondria against ferroptosis.

Huan Chen, Xi-Chen Li, Yi Yuan et al. · Antioxidants · 0 citations