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Author

Xiao-Ming Luo

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Sep 2026

6PPDQ exposure enhances susceptibility to ulcerative colitis by disturbing MMP9, PTGS2, and PPARG homeostasis: an integrative network toxicology and in vivo study.

The tire-derived contaminant 6PPD-quinone (6PPDQ) is widespread in the environment and exhibits intestinal toxicity, yet its role in ulcerative colitis (UC) remains unclear. This study integrated network toxicology, bioinformatics, molecular docking, and in vivo experiments to investigate whether 6PPDQ exposure increas...

Xiong Li, Xiao-Ting Xu, Yun-Sun Cai et al. · 0 citations

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