Author

Xiao-Nan Ma

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Open access Sep 2026

Enhancing METTL3-mediated m6A modification of Fzd3 mRNA exhibits neuroprotection in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder characterized by progressive loss of motor neurons (MNs). N 6 -methyladenosine (m 6 A) is the most abundant mRNA modification, yet its role in ALS MNs degeneration remains poorly understood. In this study we observed a significant...

Jinmeng Liu, Qiu Yan, Ying-Jun Guan et al. · Cell Death & Disease · 0 citations

Review Open access Aug 2026

Lactate Metabolism and Signaling in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease characterized by the selective degeneration of upper and lower motor neurons (MNs). Although the specific pathogenesis of ALS is not yet fully understood, there is increasing evidence that abnormal energy metabolism plays a key rol...

Xiao-Nan Ma, Jinmeng Liu, Ying-Jun Guan et al. · Cells · 0 citations