Open access
Aug 2026
A Live Attenuated AP2X-1-Deficient Toxoplasma Strain Confers Protective Immunity Against Acute and Chronic Toxoplasmosis in a Murine Model
PruΔap2X-1 represents a potential live-attenuated vaccine candidate against toxoplasmosis, with a favorable safety profile observed under the experimental conditions, and induces a strong Th1-biased cellular and humoral immune response.
Wen-Bo Hao, Li-Xiu Sun, Ru-Shi Tu et al.
· Animals · 0 citations