Xiao-Ping Gu

Morphological plasticity facilitates lung adaptation and dynamic immune remodeling in Mycobacterium abscessus infection

Summary Mycobacterium abscessus pulmonary disease (Mab-PD) shows rising global incidence and low cure rates. Mab exhibits marked phenotypic heterogeneity, with infection outcomes likely dependent on strain-specific host interactions. Through in vivo morphotype switching, we obtained a rough strain (Mab-R) that showed h...