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Author

Xiao-Qing Lian

2 papers indexed here

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Preprint Oct 2026

Panoramic modelling of single-cell transcriptomes at scale with CellNet

Comprehensively characterizing cellular diversity is critical for understanding tissue development, identifying disease-associated populations and investigating gene programmes linked to specialized functions. Advances in single-cell profiling reveal additional cell-specific transcripts and molecular associations, yet...

Xiao-Qing Lian, Pei Liu, Jia-Hui Tan et al. · 0 citations
Open access Sep 2026

UpTCR: a unified progressive knowledge transfer foundation model for robust T-cell receptor-antigen binding recognition

T-cell receptor (TCR) recognition of antigenic peptides presented by human leukocyte antigen (HLA) molecules underpins adaptive immunity and T cell-based immunotherapy. However, the scarcity of complete interaction data and TCR cross-reactivity challenge robust prediction. Here, we present UpTCR, a unified progressiv...

Tian-Xu Lv, Yang Xiao, Li Chen et al. · 0 citations

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