Xiao-Qing Xie

Cancer-associated fibroblasts in triple-negative breast cancer: heterogeneity, tumor-stroma crosstalk, and therapeutic resistance

Triple-negative breast cancer (TNBC) comprises a clinically and biologically heterogeneous group of breast cancers defined by the absence of estrogen receptor and progesterone receptor expression and the lack of human epidermal growth factor receptor 2 (HER2) overexpression or amplification. Although systemic treatment...