Author

Xiao-Qun Li

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Review Open access Sep 2026

Neuroprotective effects and mechanistic insights of sinomenine in ischemic stroke: a systematic review and meta-analysis of preclinical animal studies

Ischemic stroke is a leading cause of long-term disability and mortality worldwide. Despite substantial advances in reperfusion therapy, effective neuroprotective strategies remain limited. Sinomenine, a bioactive alkaloid derived from plants of the Menispermaceae family, has shown neuroprotective effects in precli...

Xiao-Qun Li, Lu-Lu Wen, Yun Du et al. · Frontiers in Pharmacology · 0 citations

Review Open access Aug 2026

Preclinical evidence of neuroprotective effects of endocannabinoids and related lipid molecules in ischemic stroke: a systematic review and meta-analysis of animal studies

The results demonstrated that eCBs and related lipid molecules significantly reduced cerebral infarct volume, improved neurological function score (NFS), and preserved blood–brain barrier (BBB) integrity, as evidenced by decreased BBB permeability and alleviated cerebral edema.

Xiao-Qun Li, Lu-Lu Wen, Yun Du et al. · European Journal of Medical... · 0 citations