Author

Xiao-Rong Zhou

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Open access Sep 2026

Immunogenic cell death and tertiary lymphoid structures jointly define dysregulated antitumor immune states and therapeutic vulnerability in lung adenocarcinoma

TLS- and ICD-related programs jointly delineate clinically significant immune states in LUAD through convergent transcriptomic, genetic, single-cell, spatial, pharmacological, and systems-level evidence, and are associated with immune microenvironment remodeling, immunotherapy responsiveness, prognosis, and therapeutic...

Yun-Tian Lu, Yi Sun, Yi-Han Meng et al. · Frontiers in Immunology · 0 citations

Open access Jul 2026

Resveratrol-activated PI3K/AKT/mTOR signaling pathway attenuates ferroptosis by promoting NRF2/GPX4 metabolic pathway to mitigate IFN-gamma-mediated aplastic anemia

RSV is a potential therapeutic drug for ferroptosis-related AA treatment by targeting the PI3K/AKT/mTOR signaling pathway, which enhances NRF2-mediated GPX4 transcription, thereby ameliorating AA symptoms in vitro and in vivo.

Erhao Zhang, Jia-Nan Cui, Xinran Zhu et al. · Chinese Medicine · 0 citations