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Open access Sep 2026

Association Between Frailty Index and New-Onset Stroke in Middle-Aged and Elderly Chinese Adults with Gastrointestinal or Liver Diseases: A Longitudinal Cohort Study

Background: Although the frailty index (FI) has been reported to associate with stroke risk in older adults, its relationship in those with gastrointestinal (GI) or liver diseases remains unclear. We examined this association in a Chinese cohort with these comorbidities. Methods: Using baseline data from the China Heal...

Xiao She, Hai-Yan Yang, Xiao Zhao et al. · 0 citations
Aug 2026

Mapping the immune-genetic architecture of Epstein-Barr virus-related phenotypes and multiple sclerosis through a single-cell genetic framework for target prioritization and pharmacologic hypothesis generation.

BACKGROUND Multiple sclerosis (MS) is a severe neuroinflammatory disease causing substantial long-term disability. Strong epidemiologic evidence links Epstein-Barr virus (EBV) exposure with MS risk, but genetic evidence for immune target prioritization in EBV-related phenotypes remains limited. METHODS We integrated...

Yi-Xiang Zhou, Xin-Di Huang, Xiao She et al. · 0 citations

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