Author

Xiao-Ting Hua

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Open access Sep 2026

Molecular epidemiology and genomic characteristics of clinical Acinetobacter baumannii isolates from patients with hospital-acquired pneumonia in China, 2019–2020: a multicentre retrospective study

Summary Background Carbapenem-resistant Acinetobacter baumannii (CRAB) is a leading cause of hospital-acquired pneumonia (HAP) with high mortality. However, large-scale nationwide data of HAP-causing CRAB in China remain limited. Methods Here, we performed a nationwide multicentre retrospective study to characterise th...

Jin-Tao He, Qing-Ye Xu, Min-Fei Peng et al. · EBioMedicine · 0 citations

Open access Sep 2026

TattleTail: A Rule-Based Tool for Identifying Canonical Pyocin-Encoding Gene Clusters in Pseudomonas aeruginosa

Tailocins are phage tail-like bacteriocins derived from prophages that have lost the ability to package viral genomes while retaining bactericidal activity against related bacterial strains. In Pseudomonas aeruginosa, these elements are referred to as pyocins and contribute to ecological fitness and antimicrobial appli...

R. G. Pais, Wei-Lian Chen, S. Leptihn et al. · Computational and Structural... · 0 citations

Open access Sep 2026

PiuA promoter mutations confer cefiderocol resistance in Acinetobacter baumannii: from in vitro evolution to global genomic screening

Introduction Carbapenem-resistant Acinetobacter baumannii (CRAB) poses a global health threat due to limited therapeutic options. Cefiderocol, a novel siderophore-conjugated cephalosporin, demonstrates potent in vitro activity against a variety of Gram-negative bacteria, including CRAB. However, cefiderocol's recent in...

Xiao-Chen Liu, Qing-Ye Xu, Jin-Tao He et al. · Frontiers in Microbiology · 0 citations