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Author

Xiao-Tong Chen

2 papers indexed here

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Sep 2026

Interkingdom remodeling of the intestinal bacteriome and virome during Toxoplasma gondii infection in rats.

Toxoplasma gondii infection is associated with intestinal microbiome disruption, but its effects on genome-resolved bacterial populations, the gut virome, and bacteriome-virome relationships remain poorly understood. Using previously generated shotgun metagenomic datasets from 36 intestinal samples collected from 18 Sp...

Meng-Ting Yang, Ting Bai, Ji-Xin Zhao et al. · 0 citations
Aug 2026

Untargeted metabolomics reveals L-Lysine depletion as a host-directed therapeutic target in Toxoplasma gondii infection.

Toxoplasmosis is a widespread zoonotic disease causing severe outcomes in immunocompromised individuals and during pregnancy. Current therapeutic options target actively replicating stages of the parasite and show limited efficacy against chronic infection. While research has focused on parasite-directed therapies, hos...

Xue-Yao Wang, Ji-Xin Zhao, Xiao-Tong Chen et al. · 1 citation

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