Author

Xiao-Wei Qi

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Open access Sep 2026

HER2-Targeted AIE Nanotheranostics Overcome SHR-A1811 Resistance via Immunogenic Pyroptosis and Tumor-Associated Macrophage Reprogramming in Breast Cancer.

Antibody-drug conjugates (ADCs) have revolutionized HER2-positive breast cancer treatment, yet resistance to next-generation agents such as SHR-A1811 (trastuzumab rezetecan) remains a major challenge arising from poor intratumoral delivery, enhanced DNA damage repair, and an immunosuppressive tumor microenvironment (TM...

Xiao-Hong Liu, Ni-Sha Wu, Zai-Hui Peng et al. · Small · 0 citations

Open access Sep 2026

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

ABSTRACT Triple‐negative breast cancer (TNBC) remains therapeutically challenging due to its aggressive metastatic potential, high recurrence rates, and lack of effective targeted therapies. Herein, we identified that SOX30 is significantly upregulated in TNBC and correlates with poor clinical prognosis. Functionally,...

Pingping Gao, N. Sun, Ning Yang et al. · Advancement of science · 0 citations