Open access
Aug 2026
Potential targets and molecular mechanisms of D-pinitol against acute kidney injury based on network pharmacology and experimental validation
Abstract Acute kidney injury (AKI) is a severe clinical syndrome, with ischemia/reperfusion (I/R) being one of its most common causes. Although D‑pinitol (DP), an inositol‑like bioactive molecule, is known to confer renal protection, its efficacy against I/R‑induced AKI remains unknown. A mouse kidney I/R model was emp...
Yi-Lin Ren, Yuan Ge, Ke-Yu Zhang et al.
· Renal Failure · 0 citations