Review
Open access
Oct 2026
Colitis-associated colorectal carcinogenesis: molecular mechanisms and therapeutic potential
Chronic colitis is a major risk factor for colorectal cancer (CRC), particularly for colitis-associated colorectal cancer (CAC), where persistent inflammation drives the transition from mucosal injury to malignant transformation. Accumulating evidence indicates that gut microbiota dysbiosis, epithelial barrier disrupti...
Yi Lu, Xi-Xi Wang, Cui-Ke Yin et al.
· Molecular Biomedicine · 0 citations