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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Xiao-Xia Gu

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2 papers indexed here

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Open access Sep 2026

Remodeling the Host Immune Microenvironment in Carbapenem-Resistant Klebsiella pneumoniae: An Evidence-Graded Framework for Host-Directed Intervention.

Klebsiella pneumoniae ranks at the top of the WHO priority pathogen list. The convergence of carbapenem resistance with hypervirulence is exhausting pathogen-directed therapy. Host-directed therapy (HDT) offers a structural alternative: because it acts on host targets, it is largely indifferent to the carbapenemases th...

Xiao Liang, Jun-Wei Wang, Chao Liu et al. · 0 citations
Open access Oct 2026

Kaurepenoid A, a 2-nor-ent-kaurane diterpenoid with P-glycoprotein-mediated reversal of multidrug resistance activity from the fungus Bipolaris sp.

Chemical research on the fungus Bipolaris sp. led to the identification of seven ent-kaurane diterpenoids, kaurepenoids A-G (1-7), marking the first isolation of such diterpenoids from this genus. Kaurepenoids A-F (1-6) represent the first 2-nor-ent-kaurane diterpenoids with a fused 5/6/6/5 tetracyclic ring system. Kau...

Yong Shen, Nan-Jin Ding, Mei-Jia Zheng et al. · 0 citations

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