Open access
Sep 2026
S100A8/A9-TMEM24 axis drives podocyte injury by impairing autophagy: a novel theranostic target for early diabetic nephropathy.
OBJECTIVE To establish a comprehensive theranostic framework for early-stage diabetic kidney disease (DKD) by validating serum S100A8/A9 as a highly sensitive diagnostic biomarker and exploring therapeutic strategies targeting the S100A9/transmembrane protein 24 (TMEM24) signaling axis to restore podocyte autophagy....
Jia-Sen Shi, Heng Wang, Liu Xu et al.
· Pharmacological Research · 0 citations