Author

Xiao-Xu Han

h-index 3 View on Semantic Scholar

We have 3 of 9 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Sep 2026

A novel PRPF31 variant associated with autosomal dominant retinitis pigmentosa in Japanese families.

BACKGROUND PRPF31-associated inherited retinal dystrophy is an autosomal dominant form of retinitis pigmentosa (RP), typically caused by haploinsufficiency. Although affected individuals generally exhibit early-onset nyctalopia and progressive visual field loss, the clinical and genetic characteristics associated with...

Wakako Okayama-Miyazaki, Akiko Yoshida, Xiao-Xu Han et al. · Ophthalmic Genetics · 0 citations

Review Open access Sep 2026

iPSC-derived retinal organoids: Biological insights and progress toward photoreceptor replacement therapy.

Induced pluripotent stem cell (iPSC)-derived retinal organoids (ROs) have emerged as a platform for photoreceptor replacement therapy, supported by two complementary approaches: cone precursor cell transplantation and RO transplantation. Both have demonstrated proof of concept for functional synaptic integration with t...

Akiko Maeda, Xiao-Xu Han, M. Mandai · Cell Reports Medicine · 0 citations

Open access Aug 2026

Single-cell spatial transcriptomics reveals rewiring of RPE and Müller glia signaling toward photoreceptors following outer segment disruption in Prph2C213Y mice.

It is indicated that PRPH2-associated retinal dystrophy is a multicellular process in which OS disruption drives coordinated RPE and Müller glial remodeling with potentially protective or pro-degenerative effects, and nominate the RPE Nfib-Fstl1 program, Müller glial AP-1 responses with predicted STAT3 involvement, and...

Haoxin Guo, Linfei Wei, Binghan Chen et al. · Neurobiology of Disease · 0 citations