MIRCID: Inferred Hub-miRNAs Drive Cross-Task Improvements in Drug Mechanistic Modeling
MIRCID, a framework comparing gene expression with inferred transcription factor activity and miRNA expression across pathway classification and similarity-based MoA retrieval, supports inferred HubmiRs as a biologically informed recoding of transcriptomic data for perturbational drug modeling, while leaving recovery o...
Xin Cao, Yi-Gang Chen, Jia-Tong Xu et al.
· bioRxiv · 0 citations