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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Xiao-Yan Huang

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Open access Jan 2026

Keap1 Deficiency Promotes Macrophage M2 Polarization and Protects β Cells

Background Progressive pancreatic β‐cell injury is a core feature of Type 2 diabetes mellitus (T2DM). Imbalance between macrophage M1 and M2 polarization, driven by chronic inflammation, is a key contributor to this injury. The Keap1‐Nrf2‐ARE pathway regulates macrophage polarization and inflammatory responses, but whe...

Bao-Liang Huang, Lun-Pan Mou, Xiao-Yan Huang et al. · 0 citations

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