Author

Xiao-Yang Feng

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Open access Sep 2026

A kynurenine immune-metabolic subtype of depression defined by childhood maltreatment and IDO2: Evidence from multi-omics profiling

Abstract Background Major depressive disorder (MDD) is a complex disorder caused by genetic and environmental factors. Previous evidence implicates a potential depression subtype from interaction between childhood maltreatment (CM) and kynurenine pathway (KP) gene. Here, we investigated the top-down multi-omics KP alte...

Yao-Yao Sun, Meng-Han Su, Z. Kang et al. · Psychological Medicine · 0 citations

Aug 2026

Higher frequencies of CNV deletions in bipolar disorder among Chinese Population.

This work delivers the most thorough delineation of BD-associated CNVs in Han Chinese to date, underscoring the imperative for ancestry-inclusive research to comprehensively unravel psychiatric genomics and unveiling fresh mechanistic perspectives on BD etiology.

Yong Wu, Xiangyu Li, Yao-Yao Sun et al. · Molecular Psychiatry · 0 citations