Curcumin-activated olfactory ensheathing cells attenuate astroglial scar to facilitate nerve repair via the IL-10/NF-κB axis after spinal cord injury.
Excessive astrocyte activation following spinal cord injury (SCI) can trigger the substantial deposition of inhibitory extracellular matrix components, particularly chondroitin sulfate proteoglycans (CSPGs) at the lesion core. This astroglial response typically leads to the formation of dense glial scars, which profoun...