Author

Xiao-Yang Zhou

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Open access Sep 2026

TET1 loss promotes malignant phenotypes in HeLa cells and is associated with altered PTEN–PI3K/AKT/mTOR signaling

Reduced TET1 expression was observed in SCC-restricted public cohorts, while TET1 depletion promoted malignant phenotypes in HeLa cells, which identifies a candidate signaling association that warrants validation through rescue experiments and locus-specific epigenetic studies.

Yang Liu, Lu-Jia Liu, Lu-Sheng Wang et al. · Frontiers in Oncology · 0 citations

Open access Aug 2026

Quercetin protects HTR-8/SVneo human trophoblast cells against oxidative stress injury via activating EGFR/PI3K/AKT-NRF2/HO-1 signaling axis

Investigating whether quercetin alleviates H2O2-induced oxidative damage in HTR-8/SVneo trophoblasts via regulating the EGFR/PI3K/AKT-NRF2/HO-1 axis provided a novel mechanism and potential intervention for adverse pregnancy outcomes.

Lu-Jia Liu, Zhixian Ding, Yi-Na Wu et al. · Frontiers in Pharmacology · 0 citations