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Xiao-Ying Zhai

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Open access Sep 2026

Impact of busulfan exposure stratification on transplant outcomes and immune reconstitution in children with severe aplastic anemia

Background Severe aplastic anemia (SAA) is a life-threatening bone marrow failure disorder. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an established curative treatment for pediatric patients with SAA. Busulfan, a key component of conditioning regimens, has a narrow therapeutic index and marked i...

Yan-Xiao Li, Xiao-Ying Zhai, Qian-Qian Zhang et al. · 0 citations

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